Recovery from Rapamycin
نویسندگان
چکیده
منابع مشابه
Rapamycin
Vaccines that generate Ag-specific CD8(+) T-cell responses of appropriate quality, magnitude and duration are highly desirable. The ability of mTOR to regulate CD8(+) T-cell functional differentiation must be exploited for clinical benefit. In a recent paper, we report that varying the regimen of rapamycin administration regulates viral vaccine-induced CD8(+) T-cell responses for tumor immunity...
متن کاملRapamycin.
Purpose of the Study Pulmonary metastasis continues to be the major cause of mortality among human and canine patients with osteosarcoma. A series of investigational agents will be evaluated in dogs with appendicular osteosarcoma with the hopes of identifying new drugs that help dogs live longer after being diagnosed with osteosarcoma. Rapamycin is a drug that may help slow down the progression...
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The immunosuppressive effect of rapamycin is mediated by inhibition of interleukin-2-stimulated T cell proliferation. We report for the first time that rapamycin also inhibits growth factor-induced proliferation of cultured mouse proximal tubular (MPT; IC(50) ~1 ng/ml) cells and promotes apoptosis of these cells by impairing the survival effects of the same growth factors. On the basis of these...
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objective: the main aim of this study was to investigate the psychological and social adjustment of parents whose adolescent children had experienced a disaster. mediating factors were considered; such as whether the child developed post-traumatic stress disorder (ptsd), dysfunctional attitudes, other intervening life events, and especially, social support. method: participants were 37 women wh...
متن کاملFunctional Recovery From Stroke
Background and Purpose Shorter lengths of hospital stay in stroke units could be due to quicker functional recovery or mechanisms of expediting hospital discharge. Methods Stroke survivors with an intermediate prognosis at 2 weeks after stroke (n=146) were randomized for management in a stroke rehabilitation unit or in general wards. Barthel scores were monitored at weekly intervals until hospi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2014
ISSN: 0021-9258
DOI: 10.1074/jbc.m114.589754